Burning sensation in feet might be also caused due to Erythromelalgia in some cases. This is also due to nerve damage and is very similar to Peripheral neuropathy. But there are some big differences between burning feet (Grierson-Gopalan Syndrome) and Erythromelalgia which helps you to easily identify the underlying cause of burning sensation in your feet and there are also some underlying conditions which causes Erythromelalgia
Erythromelalgia is also very similar to burning feet but there are key signs which differentiate Erythromelalgia from burning feet (Grierson-Gopalan Syndrome). It can cause intense episodes of burning pain and redness in your feet sometimes the redness and burning pain might also occur in your hands, arms, legs, ears and face. The key difference here is the redness that accompanies the burning sensation in your feet whereas in the Burning feet syndrome, it’s usually burning sensation which is only restricted to feet and ankles!
Some people might have erythromelalgia from early childhood whereas someone are only affected as adults. Erythromelalgia can also cause swelling in different parts of your body which might also include your hands and feet. Erythromelalgia is usually triggered by increase in your body temperature or sometimes it might be also triggered when you eat spicy foods or after having alcohol. This can be also triggered when you wear warm socks, gloves, very tight foot wear. Pain can vary from person to person as far as Erythromelalgia is concerned. It might be also accompanied by sweating in the affected area.
The best way to rule out erythromelalgia is to undergo Vitamin B deficiency tests. If you have Vitamin B deficiency, then the burning sensation in your feet might be due to Grierson-Gopalan syndrome rather than erythromelalgia which is form of peripheral neuropathy as nerves are getting affected.
The main reason for erythromelalgia is due to mutation in SCN9A gene. Nearly 15% of erythromelalgia cases are caused to due to these mutations in SCN9A gene. Erythromelalgia sometimes results from an underlying condition, such as a blood disorder – like polycythaemia, peripheral neuropathy, multiple sclerosis (MS) and autoimmune problems such as lupus or rheumatoid arthritis